The River Oaks home of Dr. Denton Cooley was built in 1948 by C.C. Rouse, with a later two-story addition designed by noted architect John Staub. Cooley, the legendary surgeon who performed the first heart transplant in the United States and the first implantation of a total artificial heart, died late last year at age 96. His wife, Louise Cooley, preceded him in death a month earlier, at age 92. The Cooleys lives in the house from 1962 until 2016.